CD274 and undifferentiated pleomorphic sarcoma: There was also diffuse CD3+ and CD8+ T-cell infiltration as well as diffuse PD-L1 expression identified in UPS tumors compared with RMS, where the majority of T cells (and PD-L1 expression) were concentrated in tertiary lymphoid structures near vascular beds, with low absolute immune cell fractions found elsewhere in the tumor [77].