KLK3 and posterior cortical atrophy: Additionally, the predictive model sharing PI-RADS score and PSA density for GG pattern > 3 was developed (see Table S6), and individualised likelihoods generated showed higher efficacy than PI-RADS and PSA density alone in the ROC curves, as their individual AUC of 0.690 (0.645–0.743) of PSAD, and 0.743 (0.702–0.784) of PI-RADS increased to an AUC of 0.777 (0.740–0.815) when both parameters were joined to predict GG > 3 in PCa.