SIRPA and neoplasm: Figure 3 shows typical cases with a low, medium, and high density of Μφ presence in the tumor stroma, expressing CD68 or SIRPα. Supplemental Figure S1 shows typical images of confocal fluorescent microscopy after triple staining for nuclei (DAPI), CD68, and SIRPα, from two tumors with the extensive presence of CD68+/SIRPα+ and CD68+/SIRPα- macrophages, respectively. Linear regression analysis showed no significant association between the SIRPα and the CD68 scores in the invading tumor front (p = 0.17) or inner tumors areas (p = 0.90).