FGFR2 and cholangiocarcinoma: A sequencing study of 115 CCA cases found that aberrations of FGFR2 are most common (6.1%, vs. 0.9% in FGFR1; 0% for FGFR3–5) with rearrangements/fusions (3.5%) more frequent than amplifications (2.6%) or mutations (0.9%) [49].