Further, we assessed how γ-H2AX and 53BP1 were associated via their expression status, as analyzed by both IHC and IF, and we found strong positive linear associations between the H-scores of γ-H2AX and 53BP1 by IHC (Figure 4A, p < 0.001, r = 0.700), and between expression percentages of tumor cells exhibiting foci of γ-H2AX and 53BP1 by IF (Figure 4B, p < 0.001, r = 0.594). This evidence concerns the gene TP53BP1 and neoplasm.