MACC1 and neoplasm: We found that MACC1 expression levels varied depending on the tumor localization with an expression that was higher in tumors from the distal part than the proximal (median: cecum = 10.18; ascending colon = 10.54, transverse colon = 10.49, descending colon = 10.46, sigmoid colon = 10.8, rectum = 10.7, Anova test: p = 5.5 × 10−5) (Figure 2B).