High MACC1 SCNAs and high expression levels were mostly observed for CIN tumors, whereas MSI, HM-SNVs and GS tumors with normal ploidy had lower MACC1 expression levels (median: CIN = 10.8, GS = 10.29, HM-SNV = 9.92, MSI = 9.65, Wilcoxon test: CIN vs. MSI: p = 1.4 × 10−10, CIN vs. GS: p = 0.0001, HM-SNV was excluded from the analysis due to small sample size) (Figure 3A, C). This evidence concerns the gene MACC1 and cervical squamous intraepithelial neoplasia.