We used a combination of immunohistochemical stainings (PD-L1, pan-cytokeratin, and CD8) and digital image analysis to characterize the immune infiltrates with a focus on tumor-infiltrating lymphocytes (TILs) and the proximity of T cells to the next located tumor cell as sign of an active relation between the tumor and the host. The gene discussed is CD8A; the disease is neoplasm.