CTNNA2 and CTNNA3. Catenin Alpha 2 and 3 (CTNNA2 and CTNNA3) were found mutated in 15% of LSCC tissues analyzed by exome sequencing by Fanjul-Fernández and colleagues, who hypothesized a tumor suppressor function for these genes. Here, CTNNA2 is linked to neoplasm.