IL6 and neoplasm: The relationship between IL-6 serum levels and both severity and LSCC extent was also analyzed by other researchers, confirming the higher levels in tumor patients (p = 0.0001) and the significant correlation with advanced stage (p < 0.0001), as well as with the occurrence of metastasis (p = 0.024) and local tumor spread (T) p < 0.0001) [192].