The prognostic potential of the Bax/Bcl2 ratio in LSCC was also analyzed by real-time qPCR, showing decreased risk of relapse and overall good prognostic outcome for patients with high Bax/Bcl2 ratio, with special reference to N0 patients, predicting for them longer DFS and OS independently from histological grade, tumor size, and TNM stage, as evidenced by Kaplan–Meier survival analysis [41]. Here, BCL2 is linked to neoplasm.