Finally, TIA1′s interaction with lncRNAs, e.g., MALAT1 and NEAT1, which display oncogenic features in HCC (Supplementary Figure S17A–C), likely also contributes to the tumor-suppressive effect of TIA1, since we could show that TIA1 silencing promotes NEAT1 upregulation in hepatic cancer cells (Supplementary Figure S17D). Here, MALAT1 is linked to neoplasm.