Interestingly, all the three selected miRNAs displaying this pattern (miR-26b-5p, miR-106b-5p, and miR-142-5p) were previously described as targeting genes involved in the TGF-β/SMAD signaling [21,22,57], a key pathway in animal cells whose misregulation can result in tumor development [25]. Here, TGFB1 is linked to neoplasm.