Whereas TGFβ induces apoptosis in some PCa cells [14], the advanced stage PCa cells adapt to TGFβ stimuli and differentiate into mesenchymal cells to evade the growth-suppressive effects of TGFβ [11,15] by a process known as epithelial-to-mesenchymal transition (EMT) [16]. This evidence concerns the gene TGFB1 and posterior cortical atrophy.