KRT7 and pachyonychia congenita: Notably soluble protein fragments of KRT7 can be detected in the circulation of cancer patients or in other fluids such as ascites [56], with the recent assessment of KRT7-positive prostatic cells in the prostatic fluid expressed during robot-assisted radical prostatectomy [60], which could lead to further liquid biopsy (circulating tumor cells) assessments in PC patients, either in blood, prostatic fluid, or urine.