Bcl2L12 expression is increased in glioblastoma through multiple mechanisms, including gene amplification (as seen as a non-focal gain of chromosome 19(q)), transcriptional upregulation in the absence of gene amplification, and induction of the Bcl2L12-targeting miR-182 [18,39,40,41,42]. This evidence concerns the gene BCL2L12 and glioblastoma.