Using a peptide derived from the melanoma gp100 antigen, Skakuj et al. generated SNAs using a liposomal core with TLR9-stimulatory CpG oligonucleotides, immobilized on the core surface through intercalation by using a cholesterol anchor and linked to a peptide derived from the gp100 model antigen [64]. The gene discussed is PMEL; the disease is melanoma.