Tumour-driven cytokines, such as growth differentiation factor 11, IL-1β, IL-6 leukaemiaia inhibitory factor, TNF-α, and TGFβ1 promote cancer cachexia with anorexia in the brain, proteolysis in the skeletal muscles, and browning in the WAT [5]. The gene discussed is TGFB1; the disease is neoplasm.