In this scenario, HT can be considered the most important player in the protective role of MOMAST® GR25 in osteoarthritis pathology since it has been able to exert direct effects on the antioxidant system by stimulating glutathione peroxidase, SOD, and glutathione reductase activities and also maintaining higher reduced glutathione (GSH) levels in cells [57,58]. This evidence concerns the gene GSR and osteoarthritis.