CD40LG and infection: Excluding the 63 participants with IgM evidence of DENV infection, there remained a total of 326 participants who tested positive for either CHIKV or ZIKV infections (or both): 213 (31%) with ZIKV mono-infection, 55 (8%) with CHIKV mono-infection, and 58 (8%) with evidence of a sequential ZIKV/CHIKV infection (Table 2).