Unexpectedly, the correlation analysis between the upstream regulator's analysis identified MYBL2, E2F2, CBX3, FOXM1, and E2F1 (Figure 5B), which were significantly elevated in the LUAD or LIHC tumor groups (Figure 5E), with a strongly correlated value (Figure 5F) with utility as biomarkers (Figure 5C, 5D). Here, E2F1 is linked to neoplasm.