BAX and Hepatic fibrosis: Results indicated that melatonin administration was able to decrease positive apoptotic cells (Choi et al., 2015; Esrefoglu et al., 2017), Bax expression (Mortezaee et al., 2017, 2018), and cleaved caspase‐3/caspase‐3 ratio (Choi et al., 2015), and induce higher levels of the antiapoptotic protein Bcl‐2 (Mortezaee et al., 2017, 2018), using different animal models with CCl4‐derived liver fibrosis.