Because the above human PDAC RNAseq data suggested that CCR2 and CCR5 were the main immunosuppressive signals on myeloid cells following αPD-1 therapy, we prioritized our RNAseq analysis on the CD11b+ myeloid cells sorted from the orthotopically implanted KPC pancreatic tumors following various treatments. The gene discussed is CCR5; the disease is pancreatic neoplasm.