GPR180 and malaria: Compared with the prefertilization TBV targets P48/45 (51), P230 (52), and HAP2 (53), as well as postfertilization targets such as P25/28 (50) and PSOP25 (49), GPR180 is expressed on both gametes and ookinetes and may elicit both pre- and postfertilization TB immunity, which encourages future studies in human malaria parasites.