Gene Set Enrichment Analysis of differentially upregulated genes in M2 versus M1 macrophages against the ranked gene list of TCGA ovarian cancer samples with high versus low expression of metadherin also showed enrichment of M2‐like macrophage signature in the metadherin‐high samples (Figure 5d). We also observed coexpression of β‐catenin and metadherin in both primary and ascitic tumor samples from ovarian cancer patients by Western blot (Figure 5e). Here, MTDH is linked to ovarian carcinoma.