CEACAM1 and neoplasm: For example, CCL3 plays a central role in the recruitment of distinct immune cells to the tumor site, dendritic cell homing, and antigen‐specific T‐cell immunity.[34]  In addition to targeting CEACAM1 and CCL3, altering the polarization state of macrophages by nanoparticles would also represent a promising direction for macrophage‐based immunotherapy given our finding that metastatic cells could induce TAM‐like phenotypes.[53, 54]