Obese older adults had a .13-unit greater increase in cystatin C than those with a normal BMI (b = 0·13, 95 % CI = 0·06, 0·20), and older adults reporting diabetes-related kidney problems had a .69-unit greater increase in cystatin C than those not reporting such problems (b = 0·69, 95 % CI = 0·15, 1·21). Here, CST3 is linked to diabetes mellitus.