The combined results of the four serum liver fibrosis indexes, LN, HA, PCIII, and CIV, suggested the synthesis of TGF-β1 inhibited by DIP might regulate the expression of CTGF and decrease the proliferation of fibrinogen and fibroblasts, which reduced the synthesis of fibroblasts to transform into myofibroblasts. The gene discussed is CCN2; the disease is Hepatic fibrosis.