CD274 and diffuse large B-cell lymphoma: In addition, Zhao and colleagues found that lncRNAs SNHG14 / microRNA miR-5590-3p/ gene ZEB1 positive feedback loop promotes progression and immune evasion of diffuse large B cell lymphoma (DLBCL) through regulating PD-1/PD-L1 checkpoint, which suggests that targeting SNHG14 could be a promising way to improve the effectiveness of DLBCL immunotherapy (36).