In the CVID group without asthma, the distribution of lower absolute numbers of CD4+ T cells (27.78%) and absolute numbers and relative values of RTE cells (both 22.22%) was noted significantly more frequent than in the CVID with asthma group (all values within the normal range, p = 0.015, p = 0.037, and p = 0.037, respectively). This evidence concerns the gene CD4 and common variable immunodeficiency.