Surprisingly, in asthmatic children with CVID, the absolute counts and percentage values of CD19+, and CD19+CD21lo B cells, RTE, Treg cells, and CXCR5+ Tfh cells were increased, but only relative values of the latter T-cell subset showed statistical significance (p = 0.040). The gene discussed is CXCR5; the disease is common variable immunodeficiency.