GHR d3 allele was associated with reduced odds of pre-hypertension and hypertension in Yixing boys (ORs [95% CIs] for the additive model and dominant model: 0.750 [0.585-0.962], P = 0.023; 0.757 [0.587-0.976], P = 0.031; Supplementary Table 3). The gene discussed is GHR; the disease is hypertensive disorder.