For the diagnosis of tuberculosis, clinical laboratory tests play an important role, although with the long culture time and the low positive rate, the culture of Mycobacterium tuberculosis is still the gold standard (Darton et al., 2017); the other common tests such as smear microscopy, purified protein derivative (PPD) test, interferon-gamma (IFN-γ) release assay (IGRA), M.tb nucleic acid test, and Xpert/MTB system are also widely used (Fan et al., 2012; Norbis et al., 2014; Fan et al., 2018). The gene discussed is IFNG; the disease is tuberculosis.