After treatment with CD44-shRNA/DDP magnetic nanoliposomes with MFH, the blood white cells of five nude mice bearing tumor were 5.9×109/L,4.7×109/L, 5.6×109/L, 4.6×109/L, and 5.8×109/L, respectively; the red cells were 3.4×1012/L, 3.6×1012/L, 3.0×1012/L, 3.4×1012/L, and 3.5×1012/L,respectively; Hb was 115, 106, 105, 103, and 98 g/L, respectively; and the platelets were 362×109/L, 306×109/L, 307×109/L, 256×109/L, and 274×109/L, respectively. Here, CD44 is linked to neoplasm.