According to Yao et al., high expression of lncRNAs (A2M-AS1, C2orf27A, and ZNF667-AS1) in GC tissues may act on hub ferroptosis-related genes, impair the activation of CD4+ T cells and Th cell infiltration, and ultimately lead to poor prognosis of GC (86). The gene discussed is CD4; the disease is gastric cancer.