The association between CCLN metastasis and 17 factors including gender, age, accompanied with Hashimoto’s thyroiditis or not, BRAF mutation status, cytologic category, multifocality, size, location, component, echogenicity, margin, shape, ratio of tall to wide, calcification, capsule involvement, depth, and US CCLN status was analyzed (Table 2). The gene discussed is BRAF; the disease is Hashimoto thyroiditis.