mTICI : Modified Thrombolysis in Cerebral Infarction Scale, NIHSS: National Institutes of Health Stroke Scale, mRS: modified Rankin Scale, ICH: Intracranial hemorrhage, tPA: Tissue plasminogen activator, MCA: Middle Cerebral Artery, ICA: Internal Carotid Artery, M1: M1 segment (sphenoidal/horizontal segment) of MCA, V4: V4 segment (intradural/intracranial part) of Vertebral Artery. The gene discussed is PLAT; the disease is stroke disorder.