FOXO1 and intervertebral disk degenerative disorder: To further elucidate the potential mechanism of the link between oxidative stress and immunity abnormality in IDD, like the ceRNA regulatory network of lncRNAs, we constructed the miRNA-mRNA-IDDRIICs regulatory network, such as miR-1184- FOXO1-neutrophils axis and miR-4533-MCL1-B_cells_memory axis.