NOX4 and ischemic stroke: In addition, we showed that nicotinamide adenine dinucleotide phosphate (NADPH) oxidase 4 (NOX4) was a target of miR-92b-3p, and NOX4 inhibition by GLX351322 protected against oxidative stress in cerebral I/R rat model and a H/R neuronal cell injury model, which indicated that miR-92b-3p/NOX4 were potential therapeutic targets for ischemic stroke.