CD4 and nonpapillary renal cell carcinoma: Interestingly, our results found that CCNA2 expression significantly related most of immune cell infiltration in ccRCC, among which CCNA2 positively correlated with several T cell types including activated CD4+ T cell, regulatory T cells, central memory CD4+ T cells, and effector CD4+ T cell while negatively correlated with immature dendritic cell and Type17 T cells.