Considering that Sema4D expression is only highly expressed in BMMCs of AML and B-ALL (Figure 2(b)), the correlation analysis was performed on Sema4D expression in BMMCs of AML and B-ALL and the soluble Sema4D level in serum, and no correlation was found (Figure 2(d)). The gene discussed is SEMA4D; the disease is acute lymphoblastic leukemia.