Lenti-Spike infection significantly increased the expression of inflammatory cytokines, including IL-1β, IL-6, and TNF-α, and chemokines, including CCL-2, CCL-3, CCL-4, and CXCL-10, whereas Lipo-hACE2 decoy significantly inhibited all these effects (Figure 2B). The gene discussed is CCL4; the disease is infection.