AFP and liver cancer: After surgery, AFP-L3, GP-73, and AFP levels in patients with primary liver cancer were significantly different from those in patients with benign liver lesions (P < 0.001), and the AUC (95% CI) for the combined detection of MRI and serum AFP-L3 and GP-73 levels in patients with surgically confirmed primary liver cancer was 0.747 (0.619-0.874), indicating a strong sensitivity of the combined detection.