IL18 and neoplasm: As shown in Figure 1A, 13 genes (GRX4, BAX, CHMP2A, PYCARD, CHMP48, IL18, CASP4, PLCG1, TP53, CASP1, CHMP6, CASP8, and CASP3) of the above genes were upregulated, and 7 genes (TIRAP, CHMP7, IL6, IRF1, CASP9, PRKACA, and CHMP3) were downregulated in the tumor group.