YTHDF1 and cancer: To study the expression difference of YTHDF1 in pan-cancer and verify the expression difference of YTHDF1 mRNA and protein between the ESCA and normal groups by cell experiment and immunohistochemical (IHC) staining experiment, the coexpression gene network of YTHDF1 in ESCA was investigated, and the possible biofunctions and signaling pathways of these genes were studied.