Interestingly, up-regulated miR-31-5p and down-regulated miR-132-3p inhibited the proliferation, invasion and migration of RA-FLS by negatively regulating WASF3 and RB1, respectively, suggested that miR-31-5p and miR-132-3p are protective factors in RA (44). Here, RB1 is linked to rheumatoid arthritis.