Compared with normal tissues, the mRNA expression of PDIA3 in GBM is most significantly upregulated (Figure 1B) across the 27 types of cancers, so we further performed western blot assay in clinical GBM samples to confirm the protein expression of PDIA3 in GBM samples compared with adjacent tissues (Figure 1C), and the result indicated that the PDIA3 protein was upregulated in GBM samples as expected. This evidence concerns the gene PDIA3 and cancer.