also has demonstrated that immune-related pathways, such as IFN-α response, IFN-γ response, and TNFA signaling-via-NFKB pathway, played irreplaceable roles in the prediction of prognosis, immune infiltration, and immunotherapy reaction of LGG patients with epilepsy (48), which could support a part of our findings. The gene discussed is NFKB1; the disease is epilepsy.