Compared to Active TB, QFT consistent negatives had lower levels of the innate pro-inflammatory IL8 promoting neutrophil chemotaxis, macrophage inflammatory protein (MIP)-1α and -1β and IP10, and the anti-inflammatory interleukin 1 receptor antagonist (IL1RA) that inhibits IL-1 effects. The gene discussed is CXCL10; the disease is tuberculosis.