The exosomes derived from HeLa cells transfected with receptor for SARS-CoV-2 angiotensin-converting enzyme 2 (ACE2) plasmid or those isolated from COVID-19 convalescent as well as healthy donor plasma were shown to contain ACE2 and neutralize SARS coronavirus infection in culture (56, 57). The gene discussed is ACE2; the disease is COVID-19.