As shown in Table 3, PD-L1 expression of CPS≥1 was significantly associated with age (CPS≥1 vs. CPS<1: 58.4 ± 12.2 vs. 56.1 ± 12.8, p=0.008), Lauren classification (CPS≥1 vs. CPS<1: intestinal/diffuse/mix: 24.8%/58.9%/16.3% vs. 34.4%/55.3%/10.3%, p=0.005), tumor size≥5 cm (CPS≥1 vs. CPS<1: 32.5% vs. 25.6%, p=0.027), CD-31 positivity (CPS≥1 vs. CPS<1: 25.2% vs. 18.0%, p=0.022), EBV positivity (CPS≥1 vs. CPS<1: 6.1% vs. 1.6%, p=0.001), Ki-67 index (CPS≥1 vs. CPS<1: 60.3% ± 23.8% vs. 52.6% ± 23.9%, p<0.001), and EOS count [CPS≥1 vs. CPS<1: 1.8 ± 1.6 (×108/L) vs. 1.6 ± 1.2 (×108/L), p=0.042]. Here, CD274 is linked to neoplasm.