Flow cytometry results show that siRNA silencing the expression of SGK3, ULK3, ERBB4, STK17B can reduce the infection efficiency of ORFV-GFP virus (Figure 5D), while siRNA silencing the expression of MST1R, PAK4, ERBB3 can increase the infection of ORFV-GFP virus efficient (Figure 5E). The gene discussed is ULK3; the disease is infection.