KCNQ2 and epilepsy: Herein, we reported two cases of KCNQ2-related epilepsy, a 5-year-old male with a paternally inherited heterozygous mutation (c.1639C>T; p.Arg547Trp), and a 10-year-old female with a de novo heterozygous mutation (c.740C>T; p.Ser247Leu), who benefited from PN treatment.