KCNQ2 and epilepsy: Whereas, trios NGS (epilepsy panel) revealed a de novo heterozygous mutation in Exon 5 of the KCNQ2 gene (NM_172107.4; NP_742105.1): c.740C>T/(p.Ser247Leu), affecting a highly conserved aminoacidic region and predicted to be deleterious in silico programs (Figure 1).