ATXN10 and spinocerebellar ataxia type 10: Through the combination of LRS technologies matched with the no-Amp approach, it has become possible to identify interruption motifs, potentially acting as phenotypic modifiers, within the tandem repeat expansion locus in ATXN10 in patients presenting with variable phenotypes not always in the spectrum of SCA10, including a Parkinson's disease (PD) phenotype (25, 26).