The nuclear receptor family has shown a percentage of 19.3% association on Salvia miltiorrhiza treatment in AKI with 11 target genes involved (AKR1B1, AR, CYP1A1, ESR1, ESR2, NR1I2, NR3C1, PGR, PPARG, RXRA, and STAT3). Here, AKR1B1 is linked to acute kidney injury.