Previous studies showed that the DUSP1 gene, as a transcriptional target of the p53 tumor suppressor, is highly expressed in prostate cancer (Hou et al., 2012) and played a vital role to inhibit tumor progression in these tumors such as prostate cancer, bladder cancer, and colon cancer (Slattery et al., 2012). This evidence concerns the gene TP53 and Familial prostate cancer.