The 2,706 downregulated genes were significantly enriched in 41 KEGG pathways (p < 0.05) (Figures 5E,F and Table 9), which included DNA replication, cell cycle, FA biosynthesis, valine, leucine and isoleucine degradation, extracellular matrix (ECM)–receptor interaction, transforming growth factor (TGF)-β signaling pathway, Fanconi anemia pathway, basal cell carcinoma, synthesis and degradation of ketone bodies, and so on. Here, TGFB1 is linked to basal cell carcinoma.