At the same time, univariate cox regression and multivariate cox regression analysis of C1QTNF6 and clinical features were carried out in tumors which suggest C1QTNF6 is independent prognostic factor in OS analysis, the multicox result demonstrate that C1QTNF6 is an independent factors associated with patients overall survival time in KIRC, LUAD, LGG, KIRP, ACC, UVM, MESO, LIHC, HNSC, which is generally consistent with the unicox results (Supplementary Figures S1A–M). Here, C1QTNF6 is linked to adrenal cortex carcinoma.